General intermediates for the synthesis of 6-C-alkylated DMDP-related natural products.
نویسندگان
چکیده
Protected L-homoDMDP en-8 and its C-6 epimer en-7 were prepared through two different pathways starting from the vinylpyrrolidine en-9. Based on the NMR and X-ray analysis, the stereochemistry of homoDMDP at C-6 was confirmed to be consistent with reported data. Compounds en-7 and en-8 are general intermediates for the synthesis of a series of 6-C-alkylated DMDP-related natural products, such as broussonetine G, homoDMDP-7-O-apioside, homoDMDP-7-O-b-D-xyloside and so on.
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ورودعنوان ژورنال:
- Molecules
دوره 18 6 شماره
صفحات -
تاریخ انتشار 2013